赵建宁，南京军区南京总医院骨科主任，主任医师，教授，南京大学、第二军医大学、南京医科大学和南方医科大学博士生导师，博士后联系导师，技术三级，文职一级，享受国务院政府特殊津贴和军队优秀人才特殊津贴。江苏省有突出贡献中青年专家，荣立三等功2次。全军骨科专业委员会副主任委员、关节外科主任委员，全国关节外科委员，髋关节外科工作委员会执委，副组长,膝关节外科工作委员会委员，全国和全军残疾人学会肢体残疾委员会副主任委员，中国医师协会骨科专业委员，关节外科常务委员，全军运动医学及关节镜学会委员，中国老年学会脊柱关节疾病专业委员会常务委员，华裔骨科学会理事，亚太人工关节学会中国分会理事。江苏省和南京市骨科专业副主任委员，江苏省中西医结合学会骨伤专业副主任委员，南京军区显微外科专业主任委员，南京军区骨科专业副主任委员等。并担任《医学研究生学报》副主编、《中华创伤骨科杂志》、《中国骨与关节损伤杂志》、《中国矫形外科杂志》、《中国骨伤》、《中华解剖与临床》、《TheJourmaiofArthroplasty》中文版杂志等杂志的常务编委和编委。主要研究方向为人工关节置换术后无菌性松动的防治和关节软骨损伤的早期诊断和修复。获国家自然科学基金等课题9项，省部级科技进步奖14项，其中二等奖6项，获国家专利6项，主译或参与编写专著6部，以第一和通讯作者发表论文300余篇，其中SCI论文42篇，总影响因子104.527，最高影响因子11.753。至今已培养25名博士生，已毕业15名，54名硕士生毕业。2016年拟招收1-2名博士后，要求博士年龄30岁以下。近5年科研情况汇总SCI文章序号论文题目杂志名称作者发表年月卷期页码1AutophagymediatedCoCrMoparticle-inducedperi-implantosteolysisbypromotingosteoblastapoptosisAutophagyIF11.753赵建宁201511122358-23692PolymorphismsinTP53areassociatedwithriskandsurvivalofosteosarcomainaChinesepopulationInternationalJournalofClinicalandExperimaentalPathologyIF1.891赵建宁2015833198-32033ThefibroblastexpressionofRANKLinCoCrMO-Particle-inducedosteolysisismediatedbyERstressandXBP1sActabiomaterialiaIF6.025赵建宁201524352-3604ERstressmediatedTiAl6V4particle-inducedperi-implantosteolysisbypromotingRANKLexpressioninfibroblastsPlosOneIF3.234赵建宁2015109e01377745ExpressionofXBP1sinFibroblastsisCriticalforTiAl6V4Particle-InducedRANKLExpressionandOsteolysisJournalofOrthopaedicResearchIF2.986赵建宁2015ONLINE6LinoleicacidinducesredbloodcellsandhemoglobindamageviaoxidativemechanismIntJClinExpPatholIF1.891赵建宁2015855044-50527TheflavonoidampelopsininhibitedcellgrowthandinducedapoptosisandG0/G1arrestinhumanosteosarcomaMG-63cellsinvitroPharmazieIF1.052赵建宁2015706388-3938Tumornecrosisfactor-likeweakinducerofapoptosisregulatesparticle-inducedinflammatoryosteolysisviathep38mitogen-activatedproteinkinasesignakingpathwayMolecularmedicinereportsIF1.554赵建宁20151211499-15059InhibitionofMicrotubuleDynamicsAffectsPodosomeBeltFormationDuringOsteoclastInductionCellBiochemistryandBiophysicsIF1.68赵建宁2015712741-74710Expressionandclinicalsignificanceofcyclooxygenase-2andmicroRNA-143inosteosarcomaExperimentalandtherapeuticmedicineIF1.269赵建宁2015962374-237811AsinglenucleotidepolymorphismintheTGF-B1gene(rs1982073C>T)maycontributetoincreasedrisksofbonefracture,osteoporosis,andosteoarthritis:ameta-analysisClinrheumatolIF1.696赵建宁20143632059-206412Exchangingreamednailingversusaugmentativecompressionplatingwithautogenousbonegraftingforasepticfemoralshaftnonunion:AretrospectivecohortstudyEditorialManagerIF0.614赵建宁2015496668-67513Osteoprotectiveeffectofcombinationtherapyoflow-doseoestradiolwithG15,aspecificantagonistofGPR30/GPERinovariectomy-inducedosteoporoticratsBioscienceReportsIF2.637赵建宁201535494-10014Endoplasmicreticulumstress-mediatedinflammatorysignalingpathwayswithintheosteolyticperiosteumandinterfacemembraneinparticle-inducedosteolysisCellandTissueResearchIF3.565赵建宁201515Anxiolytic-likeeffectsoftranslocatorprotein(TSPO)ligandZBD-2inananimalmodelofchronicpainMolecularpainIF3.654赵建宁201516OsteoprotectiveeffectsofestrogenmembranereceptorGPR30inovariectomizedratsThejournalofsteroidBiochemistryandMolecularBioiogyIF3.628赵建宁2015154237-24417Associationsofpoiymorphismainthebonemorphogeneticprotein-2genewithriskandprognosisofosteosarcomainaChinesepopulationTumorBioIF3.611l赵建宁20153632059-206418ComparingAccuracyofCervicalPedicleScrewplacementbetweenaGuidanceSystemandManualManipulation:ACadaverstudyMedSciMonitIF1.433赵建宁2015212672-267719Sox4enhanceschondrogenicdifferentiationandproliferationofhumansynovium-derivedstemcellviaactivationoflongnoncodingRNADANCRJournalofMolecularHistologyIF1.815赵建宁2015466467-47320Tumor-SuppressingEffectsofmiR-141inHumanOsteosarcomaCellBiochemistryandBiophysicsIF2.38赵建宁201469319-32521Tumor-SuppressingEffectsofmiR-451inHumanOsteosarcomaCellBiochemistryandBiophysicsIF2.38赵建宁201470215-22422Down-RegulationofmiR-3928PromotedOsteosarcomaGrowthCellBiochemistryandBiophysicsIF2.38赵建宁201469163-16823LearningCurveofFull-EndoscopicTechniqueThroughInterlaminarApproachforL5/S1DISKherniationsCellBiochemistryandBiophysicsIF2.38赵建宁2014331547-155624ExpressionofMatrixMetalloproteinasesisPositivelyRelatedtotheSeverityofDiscDegenerationandGrowingAgeintheEastAsianLumbarDiscHerniationPatientsCellBiochemistryandBiophysicsIF2.38赵建宁2014181069-107225QuantitativeAssessmentoftheAssociationBetweenHDMXPolymorphismandSarcomaCellBiochemistryandBiophysicsIF2.38赵建宁2014158577-857926CorrelationofMatrixMetalloproteinases-1andTissueInhibitorofMetalloproteinases-1withPatientAgeandGradeofLumbarDiskHerniationCellBiochemistryandBiophysicsIF2.38赵建宁2014701219-122527ResearchProgressontheLivinGeneandOsteosarcomasAsianPacificJournalofCancerPreventionIF1.5赵建宁2014701671-167628Tumor-SuppressingEffectsofmiR-429onHumanOsteosarcomaCellBiochemistryandBiophysicsIF2.38赵建宁201469439-44429Down-RegulationofAdiponectinReceptorsinOsteoarthriticChondrocytesCellBiochemBiophysIF2.38赵建宁201470491-49730MiR-143inhibitsEGFR-signaling-dependentosteosarcomainvasionTumorBiolIF2.84赵建宁20143512743-1274831Particle-inducedosteolysismediatedbyendoplasmicreticulumstressinprosthesislooseningBIOMATERIALSIF8.312赵建宁201334112611-262332ReplytocommentonBaoetal.:LessertrochantericosteotomyintotalhiparthroplastyfortreatingCROWEtypeIVdevelopmentaldysplasiaofhipINTERNATIONALORTHOPAEDICSIF2.319赵建宁2013375987-98733LessertrochantericosteotomyintotalhiparthroplastyfortreatingCROWEtypeIVdevelopmentaldysplasiaofhipINTERNATIONALORTHOPAEDICSIF2.319赵建宁2013373385-39034FreefattyacidsareresponsibleforthehiddenbloodlossintotalhipandkneearthroplastyMedicalHypothesesIF1.054赵建宁20133104-10735SignificantpathwaysdetectioninOsteoporosisbasedonthebibliometricnetworkEUROPEANREVIEWFORMEDICALANDPHARMACOLOGICALSCIENCESIF1.093赵建宁20131711-736MicroRNAsinosteosarcoma:Frombiologicalplayerstoclinicalcontributors,areviewJOURNALOFINTERNATIONALMEDICALRESEARCHIF0.958赵建宁20134111-1237DesignandpreliminarybiomechanicalanalysisofartificialcervicaljointcomplexArchivesoforthopaedlcandtraumasurgeryIF1.358赵建宁20131336735-74338ThecanonicalWnt-beta-cateninpathwayindevelopmentandchemotherapyofosteosarcomaFrontiersinBioscienceIF3.286赵建宁2013611384-139139CaMKIIactivatesASK1toinduceapoptosisofspinalastrocytesunderoxygen-glucosedeprivationCellularandmolecularneuroblologyIF0.98赵建宁2013334543-54940SystematicscreenwithkinasesinhibitorsrevealakinasesplaydistinctrolesingrowthofosteoprogenitorcellsIntJClinExppatholIF2.242赵建宁20136102082-209141SimultaneousregenerationofarticularcartilageandsubchondralboneinvivousingMSCsinducedbyaspatiallycontrolledgenedeliverysysteminbilayeredintegratedscaffoldsBiomaterialsIF8.312赵建宁201134科研课题序号项目名称项目来源经费（万）完成人起止时间1磨损微粒诱导的成骨细胞自噬在关节假体周围无菌性松动发病中的作用及机制研究81572111国家自然科学基金57赵建宁2016.1-2019.122内质网应激抑制剂4-Phenylbutyrate（4-PBA）减轻磨损微粒诱导骨溶解的机制研究南京市科研课题5赵建宁2014.1-2017.13江苏省骨科临床研究中心江苏省科技厅150赵建宁2012.5-2015.124抗假体松动骨水泥的研制及其抑制关节置换后骨溶解中的作用江苏省自然基金10赵建宁2012.7-2015.65抗假体松动骨水泥的研制及其抑制关节置换后骨溶解的机制研究军区重点课题20赵建宁2012.1-2014.12